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Journal of Accident & Emergency Medicine 1994;11:178-182; doi:10.1136/emj.11.3.178
© 1994 BMJ Publishing Group Ltd and the College of Emergency Medicine.

Evaluation of topical ibuprofen cream in the treatment of acute ankle sprains.

J Campbell, T Dunn

Accident and Emergency Department, St John's Hospital at Howden, Livingston.

One hundred patients who presented to the accident and emergency (A&E) department with an acute ankle sprain were entered into a study to determine the efficacy of topical ibuprofen cream by using a double-blind placebo controlled design in a single type of soft-tissue injury. The subjects were given either topical ibuprofen cream or a placebo cream in addition to the standard management of the department. Patients kept diaries recording walking ability and pain visual analogue scales for resting, standing and walking. A total of 51 patients returned diaries that were suitable for analysis. Patients using the topical ibuprofen cream had significant reduction in pain scores over the first 48 h of treatment.


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This article has been cited by other articles:

  • Bleakley, C M, McDonough, S M, MacAuley, D C, Bjordal, J (2006). Cryotherapy for acute ankle sprains: a randomised controlled study of two different icing protocols * Commentary. Br. J. Sports. Med. 40: 700-705 [Abstract] [Full Text]  

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