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Emergency Medicine Journal 2003;20:560-561; doi:10.1136/emj.20.6.560
© 2003 BMJ Publishing Group Ltd and the College of Emergency Medicine.

CASE REPORT

Sustained release bupropion overdose: an important cause of prolonged symptoms after an overdose

F Jepsen1, J Matthews1, F J Andrews2

1 Accident and Emergency Department, Whiston Hospital, Prescot, UK
2 Intensive Care Department, Whiston Hospital

Correspondence to:
Correspondence to:
Dr F Jepsen
Accident and Emergency Department, Whiston Hospital, Prescot L35 5DR, UK; fjepsen{at}bigfoot.com

ABSTRACT

The case is reported of a patient who had taken a deliberate overdose of sustained release bupropion. The patient suffered from prolonged symptoms including seizures before fully recovering. The prescription of bupropion is encouraged as an aid to smoking cessation and it is probable that bupropion overdose will become more common. Emergency departments need to be aware that patients taking an overdose of sustained release bupropion may have a delayed onset and prolonged course of symptoms. The pharmacology, clinical features, and treatment of bupropion overdose are discussed.

Keywords: bupropion; overdose; seizures


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This article has been cited by other articles:

  • Rissmiller, D. J., Campo, T. (2007). Extended-Release Bupropion Induced Grand Mal Seizures. JAOA: Journal of the American Osteopathic Association 107: 441-442 [Abstract] [Full Text]  

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