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Emergency Medicine Journal 2004;21:200-203
© 2004 BMJ Publishing Group Ltd and the College of Emergency Medicine.

BEST EVIDENCE TOPIC REPORT

Antibiotics in acute exacerbations of chronic obstructive pulmonary disease

Ross Murphy, Specialist Registrar, Martin McKechnie, Specialist Registrar and Joel Dunning, RCS Fellow

Department of Emergency Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK; kevin.mackway-jones{at}man.ac.uk

Report by Ross Murphy, Specialist Registrar
Checked by Martin McKechnie, Specialist Registrar
Joel Dunning, RCS Fellow

ABSTRACT

A short cut review was carried out to establish whether antibiotics improve recovery in patients with acute exacerbations of COPD. Altogether 200 papers were found using the reported search, of which four presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results, and study weaknesses of these best papers are tabulated. A clinical bottom line is stated


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