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Emergency Medicine Journal 2005;22:599-600; doi:10.1136/emj.2002.004036
© 2005 BMJ Publishing Group Ltd and the College of Emergency Medicine.

CASE REPORT

Troponin for prediction of cardiovascular collapse in acute colchicine overdose

C van Heyningen and I D Watson

University Hospital Aintree, Liverpool, L9 7AL

Correspondence to:
Correspondence to:
Dr C van Heyningen
University Hospital Aintree, Liverpool L9 7AL, UK; charles.vanheyningen{at}aht.nwest.nhs.uk

ABSTRACT

The use of colchicine, a treatment for acute gout and familial Mediterranean fever, is limited by its toxicity. A relatively low dose of colchicine may be fatal. After a colchicine overdose, monitoring should include 6–12 hourly serum troponin measurements. A rising troponin level predicts cardiovascular collapse and is an indication for more intensive management.

Abbreviations: Tn I, troponin I

Keywords: Cardiovascular collapse; colchicine overdose; troponin


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eLetters:

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Serial Troponin-I measurements are unlikely to be useful in acute colchicine toxicity
David M WOOD, et al.
EMJ Online, 15 Aug 2005 [Full text]
Authors' response
Charles van Heyningen, et al.
EMJ Online, 29 Sep 2005 [Full text]

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