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Emergency Medicine Journal 2007;24:e12; doi:10.1136/emj.2006.042630
© 2007 BMJ Publishing Group Ltd and the College of Emergency Medicine.

EMERGENCY CASEBOOK

A case of clozapine-induced paralytic ileus

Sandeep Rondla, Steven Crane

Emergency Department, York Hospital, York, UK

Correspondence to:
Correspondence to:
Dr S Crane
Emergency Department, York Hospital, Wigginton Road, York Y031 8HE, UK; steven.crane{at}york.nhs.uk

ABSTRACT

Clozapine is a prototypical second-generation antipsychotic, which has been found to be associated with various adverse effects. Although emphasis has mainly been placed on its haematological and metabolic side effects, less attention has been paid to its anticholinergic effects. One such problem is that of a paralytic ileus. A case of a young man with psychosis who developed a paralytic ileus while on treatment with clozapine is described here.


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This article has been cited by other articles:

  • Dahmen, M. M., Stoner, S. C., Khan, R. (2009). Successful Clozapine Rechallenge Following Surgical Repair of a Bowel Obstruction. Journal of Pharmacy Practice 22: 196-199 [Abstract]  

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