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Journal of Accident & Emergency Medicine 2000;17:402-403; doi:10.1136/emj.17.6.402
© 2000 BMJ Publishing Group Ltd and the College of Emergency Medicine.
J Accid Emerg Med 2000; 17:402-403
© 2000 the Emergency Medicine Journal

Best evidence topic report

Low molecular weight heparin or unfractionated heparin in the treatment of patients with uncomplicated deep vein thrombosis

Beverley Lane, Magnus Harrison

Department of Emergency Medicine, Manchester Royal Infirmary, Oxford Road,Manchester M13 9WL

Report by Beverley Lane, Research Nurse Search checked by Magnus Harrison, Research Fellow

Clinical scenario

A 60 year old man presents with a three day history of pain in his left calf. You suspect an above knee deep vein thrombosis (DVT), which is later confirmed by ultrasound. You are considering admitting this man for treatment with unfractionated heparin (UH), when one of your colleagues mentions that low weight molecular weight heparins (LMWH) have been proven to be as good at treating thromboembolic disease and its complications. You wonder whether this is true.

Three part question

In [patients with deep vein thrombosis] is [low molecular weight heparin as good as unfractionated heparin} at {treating uncomplicated proximal DVT]?

Search strategy

Medline 1966–07/00 using the OVID interface. (Exp venous thrombosis OR deep vein thrombosis.mp) OR dvt.mp) OR [(exp thrombosis or thrombosis.mp) AND (exp veins OR Vein$.mp)] AND (exp. heparin, low molecular weight OR low molecular weight heparin.mp) NOT (prophylaxis.mp OR primary prevention.mp) LIMIT to human AND english language.

Search outcome

Altogether 373 papers identified of . . . [Full text of this article]


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This article has been cited by other articles:

  • Russell, M., Dawson, D. (2004). Low molecular weight heparin for intravenous drug users with deep vein thrombosis. Emerg. Med. J. 21: 711-711 [Abstract] [Full Text]  

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