BEST EVIDENCE TOPIC REPORT
Use of Heliox in the management of acute exacerbation of COPD
The Queen Elizabeth Hospital, King’s Lynn
Report by Dhananjay Kumar, SpR in Emergency Medicine
Checked by Rajesh Kumar Saksena, SpR in Medicine
The Queen Elizabeth Hospital, King’s Lynn
| The first 150 words of the full text of this article appear below. |
In [patients with acute COPD] does [the administration of heliox] improve [survival, Peak flow, reduce time in hospital or reduce the need for mechanical ventilation]?
A 45-year-old male smoker attends the emergency department with exacerbation of chronic obstructive pulmonary disease. Repeated doses of nebulised Salbutamol and Ipratropium Bromide has been administered and Aminophyllin infusion has been commenced. You feel that the patient will require intubation and ventilation. You have got access to Heliox and you feel that it might improve the condition of the patient and might avoid intubation. Is there any evidence to support use of Heliox in such situation?
Medline (1951 to date) Embase (1974 to date)
Dialog Datastar web (Athens) search terms [HELIUM#.W..DE., OXYGEN#.W..DE. and PULMONARY-DISEASE-CHRONIC-OBSTRUCTIVE#.DE.]-
Cochrane Library: Heliox
Reference review: A search of references from articles found by electronic searching was done.
BOC Medical Group: (manufacturer firm for Heliox) was contacted. No new articles found.
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