BEST EVIDENCE TOPIC REPORTS
BET 2 C-REACTIVE PROTEIN OR LACTATE DEHYDROGENASE TO ASSESS THE SEVERITY OF PANCREATIC NECROSIS
| The first 150 words of the full text of this article appear below. |
Report by: Charleen Liu and Charlotte Haldene, Medical Students
Search checked by: John Butler Consultant
Institution: Manchester Royal Infirmary, Manchester, UK
A short-cut review was carried out to establish whether C-reactive protein (CRP) or lactate dehydrogenase (LDH) levels were better at assessing the severity of pancreatic necrosis in patients with acute pancreatitis. A total of 29 papers was found using the reported searches, of which five presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are tabulated. It is concluded that CRP appears to be better than LDH at detecting necrosis in the first 3 days of acute pancreatitis. By day 5, LDH is the most reliable predictive test.
A 50-year-old man presents to the emergency department with epigastric pain. Acute pancreatitis was diagnosed by routine diagnostic
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Pancreas and biliary tract
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Clinical diagnostic tests
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Radiology (diagnostics)
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Pain (neurology)
- Radiology
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