BEST EVIDENCE TOPIC REPORTS
BET 3 TRAINING AND PRESCRIPTION OF NALOXONE FOR PERSONAL USE IN OVERDOSE FOR OPIATE ADDICTS
| The first 150 words of the full text of this article appear below. |
Report by: Jenifer Barrie, Medical Student
Search checked by: Kevin Mackway-Jones, Consultant
Institution: Manchester Royal Infirmary, Manchester, UK
A short-cut review was carried out to establish whether the training of intravenous drug users in the use of naloxone and the prescription of that drug to those users reduces mortality from opiate overdose. A total of 87 papers was found using the reported searches, of which three presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are tabulated. It is concluded that there is a lack of sound evidence to suggest that the benefits of take-home naloxone outweigh the risks. Careful evaluation of local circumstances is necessary when considering this option.
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