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Emergency Medicine Journal 2008;25:688-689; doi:10.1136/emj.2008.065698
© 2008 BMJ Publishing Group Ltd and the College of Emergency Medicine.

BEST EVIDENCE TOPIC REPORTS

BET 3 TRAINING AND PRESCRIPTION OF NALOXONE FOR PERSONAL USE IN OVERDOSE FOR OPIATE ADDICTS

The first 150 words of the full text of this article appear below.

Report by: Jenifer Barrie, Medical Student

Search checked by: Kevin Mackway-Jones, Consultant

Institution: Manchester Royal Infirmary, Manchester, UK

A short-cut review was carried out to establish whether the training of intravenous drug users in the use of naloxone and the prescription of that drug to those users reduces mortality from opiate overdose. A total of 87 papers was found using the reported searches, of which three presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are tabulated. It is concluded that there is a lack of sound evidence to suggest that the benefits of take-home naloxone outweigh the risks. Careful evaluation of local circumstances is necessary when considering this option.

Clinical scenario

An ambulance arrives at the emergency department with a patient who is said to have taken . . . [Full text of this article]


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The journal is co-owned by and the official journal of College of Emergency Medicine

Official journal of British Association for Immediate Care: BASICS, Faculty of Pre-Hospital Care, Irish Society for Immediate Care and Swedish Society for Emergency Medicine: SweSEM

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