BEST EVIDENCE TOPIC REPORTS
BET 2. USE OF INTRAVENOUS OMEPRAZOLE IN GASTROINTESTINAL PATIENTS BEFORE ENDOSCOPY
| The first 150 words of the full text of this article appear below. |
Report by: C K Tai
Search checked by: Colin A Graham, Professor
Institution: Prince of Wales Hospital, Hong Kong
A short-cut review was carried out to establish whether intravenous omeprazole should be given to patients with acute upper gastrointestinal bleeding before endoscopy. A total of 87 papers was found using the reported search, of which one represented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of this best paper is tabulated. The clinical bottom line is that there is currently insufficient evidence to support the routine use of intravenous omeprazole pre-endoscopy.
Does [intravenous omeprazole] lead to [a decrease in the rebleeding rate] for [patients with suspected gastrointestinal bleeding in the emergency department]?
A 55-year-old woman presents to the emergency department with fresh malaena. She is haemodynamically unstable. You wonder whether the
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