LETTERS
Cut-off values for B-type natriuretic peptides in the Korean population
Royal Surrey County Hospital, Guildford, Surrey, UK
Correspondence to:
J Woods, Royal Surrey County Hospital, Egerton Road, Guildford, Surrey, UK; justinwoods@doctors.org.uk
Accepted 20 September 2007
| The first 150 words of the full text of this article appear below. |
We would like to thank the authors for their contribution to the debate concerning the diagnostic use of natriuretic peptides. As a component of an integrated diagnostic scheme1 their further insight into variations in levels is helpful; however, some clarification is required and the results should be interpreted with a degree of circumspection. Choi et al2 have separated their patients into two cohorts, in those without underlying disease a significant and important group with pneumonia and sepsis were included. The reported mean value could be biased by the inclusion of this group as myocardial dysfunction caused by sepsis causes raised levels of natriuretic peptides and can be used to differentiate survivors and non-survivors.1 3 They also have not reported whether there were any echocardiographic changes of left ventricular hypertrophy or right ventricular dysfunction in either cohort, which could be associated with minor or moderate increases in brain natriuretic peptide (BNP). In
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