BEST EVIDENCE TOPIC REPORTS
BET 5: IS DANTROLENE THE BEST WAY TO TREAT HYPERTHERMIA IN PATIENTS WITH COCAINE ABUSE?
Bristol Royal Infirmary, Bristol, UK
| The first 150 words of the full text of this article appear below. |
Report by Dr Joanne Probert, Clinical Fellow Emergency Medicine
Search checked by Dr Jacqui Macnair, Clinical Fellow Emergency Medicine
Institution: Bristol Royal Infirmary, Bristol, UK
A 26-year-old man attends the emergency department having recently used cocaine. He is hyperthermic. You have heard that dantrolene may have a place in the management of hyperthermia in other situations and wonder whether it would be useful now.
In [patients who are hyperthermic following cocaine abuse] is [adding dantrolene more effective than benzodiazepines alone] at [reducing temperature].
Ovid MEDLINE(R) 1950 to March Week 2 2008. OVID EMBASE 1980 to 2008 Week 11 [dantrolene.mp. or exp Dantrolene/or benzodiazepines.mp. or exp Benzodiazepines/or exp Diazepam/or diazepam.mp.] AND [fever.mp. or exp Fever/or exp Temperature/or temperature.mp. or exp Body Temperature/or exp Hyperthermia, Induced/or hyperthermi$.mp. or pyrexia.mp.] AND [exp Cocaine-Related Disorders/or cocaine.mp. or exp Cocaine/]. The Cochrane Library Issue 1 2008. MeSH descriptor Dantrolene explode all trees 27
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