BEST EVIDENCE TOPIC REPORTS
BET 2. STEROIDS IN CHILDREN WITH ERYTHEMA MULTIFORME
Booth Hall Children’s Hospital, Manchester, Manchester, UK
| The first 150 words of the full text of this article appear below. |
Report by Mark Riley, ST3 in Emergency Medicine
Search checked by Rachel Jenner, Consultant in Emergency Medicine
Institution: Booth Hall Children’s Hospital, Manchester, Manchester, UK
A short-cut review was carried out to establish whether steroids are of any benefit in children with erythema multiforme. From a search of 136 papers only two presented controlled evidence addressing the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The clinical bottom line is that early brief high-dose steroids may be of benefit in erythema multiforme major. Steroids are not recommended in erythema multiforme minor.
In [children with erythema multiforme] do [steroids] improve [outcome]
You see an 8-year-old girl who developed a widespread rash that appears to be target lesions after a viral upper respiratory tract infection. You make a diagnosis of erythema multiforme. You
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