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Emergency Medicine Journal 2009;26:734-735; doi:10.1136/emj.2009.082461
© 2009 BMJ Publishing Group Ltd and the College of Emergency Medicine.

BEST EVIDENCE TOPIC REPORTS

BET 1. SUBLINGUAL ADRENALINE TABLETS: HOW FEASIBLE IS THIS NOVEL APPROACH TO THE TREATMENT OF ACUTE ALLERGIC REACTIONS?

The first 150 words of the full text of this article appear below.

Report by: Deepak Doshi, Specialist Registrar in Emergency Medicine

Search checked by: Bernard A Foëx, Consultant in Emergency Medicine and Critical Care Aesthetics

Institution: Manchester Royal Infirmary, Manchester, UK

A short-cut review was carried out to establish whether sublingual adrenaline tablets might be useful in the management of acute allergic reactions. Three animal studies and one case report were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are shown in table 1. The clinical bottom line is that sublingual adrenaline tablets may have a future in clinical practice but first we need clinical trials of their safety and efficacy.


 

THREE-PART QUESTION

In a [patient with an acute allergic reaction] does [a sublingual adrenaline tablet as compared to an intramuscular injection] work [better at reversing symptoms and preventing adverse effects . . . [Full text of this article]


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Official journal of British Association for Immediate Care: BASICS, Faculty of Pre-Hospital Care, Irish Society for Immediate Care and Swedish Society for Emergency Medicine: SweSEM

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