BEST EVIDENCE TOPIC REPORTS
BET 3. ENDOTRACHEAL ADRENALINE IN INTUBATED PATIENTS WITH ASTHMA
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Report by: Timothy Nutbeam, ST3 Emergency Medicine
Search checked by: Anna Fergusson, CT1 Anaesthetics
Institution: University Hospital of Coventry and Warwick, Coventry, UK
A 20-year-old man presents to the emergency department in extremis. He is known to have asthma. He is treated according to British Thoracic Society guidelines and has a rapid sequence induction with subsequent intubation. He is difficult to ventilate, due to high airway pressures (pneumothorax has been excluded). You wonder if he would benefit from endotracheal epinephrine?
Does [endotracheal epinephrine] lead to a [decrease in mortality] for [patients with asthma in extremis].
OvidSP MEDLINE 1950 to January Week 2 2009. [exp Epinephrine/OR adrenaline.mp.] AND [exp Intubation, Intratracheal/OR endotracheal.mp.] AND [exp Asthma]. Limit to humans AND English language 6.
Embase 1980 to Present. [exp adrenaline/OR epinephrine.ti.ab.] AND [exp Endotracheal Intubation/OR exp endotracheal tube/] AND [exp Asthma].
The Cochrane Library Issue 1 2009. [MeSH descriptor Epinephrine explode
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