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Emergency Medicine Journal 2009;26:616-617; doi:10.1136/emj.2009.077784
© 2009 BMJ Publishing Group Ltd and the College of Emergency Medicine.

BEST EVIDENCE TOPIC REPORTS

BET 3. DO ROUTINE PARACETAMOL LEVELS NEED TO BE TAKEN IN ALL PATIENTS PRESENTING WITH OVERDOSE?

The first 150 words of the full text of this article appear below.

Report by: Tom Leckie, Consultant in Emergency Medicine

Institution: Royal Oldham Hospital, Oldham, UK

Checked by: Kerstin Hogg, Clinical Lecturer Emergency Medicine

Institution: Salford Royal Hospital, Salford, UK

THREE-PART QUESTION

In [alert cooperative adults who present following overdose] do [paracetamol levels] detect [unsuspected paracetamol overdoses requiring treatment]?

CLINICAL SCENARIO

A 22-year-old woman attends the emergency department immediately following a deliberate ingestion of eight ibuprofen tablets. You have no reason to doubt her story of impulsive overdose taken with suicidal intent. You wonder whether her management should include 4-h paracetamol levels.

SEARCH STRATEGY

Medline 1950 to April Week 3 2009 via OVID interphase: ({[overdose.mp or exp overdose or deliberate self harm.mp. or exp self-injurious behaviour] AND [paracetamol.mp or acetaminophen.mp or exp acetaminophen] limit to "diagnosis(sensitivity)"} OR {[overdose.mp or exp overdose or deliberate self harm.mp. or exp self-injurious behaviour] AND [paracetamol.mp or acetaminophen.mp or exp acetaminophen] limit to "clinical prediction guides (sensitivity)"}) limit to adult and . . . [Full text of this article]


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