ABSTRACTS FOR VENOUS THROMBOEMBOLISM, FREE PAPER SESSION
Abstracts for Venous Thromboembolism, Free Paper Session, Thursday 17 September 10.30–11.15, Pippard Lecture TheatreIschaemia modified albumin: a new biomarker for the diagnosis of venous thromboembolism?
Salford Royal Hospital
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Background
Venous thromboembolism (VTE) including deep vein thrombosis (DVT) and pulmonary embolism (PE) is responsible for 32 000 deaths in hospitalised patients every year in the UK. Initial investigation of patients with suspected VTE recommends clinical probability score and D-dimer blood test. The Thromboembolism Assessment and Diagnosis (THREAD) study is a prospective diagnostic VTE study which aims to assess new blood biomarkers which may simplify the current diagnostic strategy for VTE. We hypothesise that ischaemia modified albumin (IMA) could be a potential diagnostic marker in DVT and PE.
Methods
The THREAD study was conducted at Salford Royal Hospital. From September 2008 to June 2009, all patients investigated for VTE in the hospital were approached to participate in the study. Each patient underwent an evidence-based reference standard diagnostic algorithm for the diagnosis and exclusion of DVT or PE, along
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