ABSTRACTS FOR RODERICK LITTLE PRIZE SESSION
Abstracts for Roderick Little Prize Session, Thursday 17 September 16.45–18.15, Great HallA multimarker strategy to exclude acute myocardial infarction: can some patients be immediately reassured?
Hope Hospital
| The first 150 words of the full text of this article appear below. |
Objective
To assess the value of eight biomarkers for the diagnosis of acute myocardial infarction (AMI) and prognostication in patients who present to the emergency department (ED) with suspected cardiac chest pain.
Methods
705 patients who presented to the ED with chest pain occurring within the previous 24 h were recruited. Blood was drawn at the time of presentation. All patients underwent 12 h troponin T testing and were followed up by telephone and chart review. Diagnostic value was assessed by receiver operating characteristic (ROC) curve analysis and a multivariate model was constructed by logistic regression.
Outcomes
A diagnosis of AMI and occurrence of adverse cardiac events (death, AMI or the need for urgent coronary revascularisation) within 30 days.
Results
Heart fatty acid binding protein (H-FABP) was found to have the best diagnostic performance of all biomarkers tested, having an area under
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