ABSTRACTS FOR RODERICK LITTLE PRIZE SESSION
Abstracts for Roderick Little Prize Session, Thursday 17 September 16.45–18.15, Great HallNormalisation of tissue oxygen saturation in ED patients with severe sepsis or septic shock is related to mortality
Leicester Royal Infirmary
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Introduction
Sepsis remains a diagnostic and therapeutic challenge. Current sepsis management guidance centres on invasive monitoring methods which are neither appropriate for every patient nor feasible in an array of clinical settings. Tissue oxygenation saturation measurement is a novel method to gain, non-invasively, information on local tissue oxygenation (normal range 80±5%). It has shown initial promising results in trauma patients, but it is not known whether it would be useful in septic ED patients.
Objective
To determine the relationship between tissue oxygen saturation (StO2) in ED patients with severe sepsis or septic shock and 30 days in-hospital mortality.
Methods
A diagnostic cohort study of adult ED patients with the clinical diagnosis of severe sepsis or septic shock. StO2 measurements were commenced as soon as possible after the patient’s arrival in the ED. The measurements continued throughout the patient’s
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