Article Text

PDF

Bronchodilator delivery in acute severe asthma in adults
  1. Stuart Teece, Research Fellow,
  2. Kevin Mackway-Jones, Professor
  1. K Mackway-Jones, Department of Emergency Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK;
  1. kevin.mackway-jones{at}man.ac.uk

Statistics from Altmetric.com

Report by Stuart Teece,Research Fellow
 Search checked by Kevin Mackway-Jones, Professor

Clinical scenario

A 24 year old known asthmatic is brought into the emergency department by friends. She has been in a smoky bar and has become very wheezy. You assess her asthma as severe. You wonder whether a nebuliser is necessary, or whether a spacer device will suffice.

Three part question

In [an adult with acute severe asthma] is [delivery of bronchodilator therapy via nebuliser or spacer] better at [impoving airflow and reducing the need for admission]?

Search strategy

Medline 1966–12/01 using the OVID interface. ([exp asthma OR asthma.mp] AND [exp bronchodilator agents OR bronchodilator$.mp] AND [exp nebulizers and vaporizers OR nebulise$.mp OR nebulize$.mp OR spacer$.mp]) LIMIT to human AND english language.

Search outcome

Altogether 1734 papers found of which two were meta-analyses that included all other relevant papers (table 6).

Table 6

Comment

The two meta-analyses have four studies (199 patients) in common.

CLINICAL BOTTOM LINE

Spacer devices can be used in place of nebulisers in patients with acute severe asthma.

Report by Stuart Teece,Research Fellow
 Search checked by Kevin Mackway-Jones, Professor

References

View Abstract

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.