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Measuring plasma paracetamol concentrations in all patients with drug overdoses; development of a clinical decision rule and clinicians willingness to use it
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- Published on: 29 April 2016
- Published on: 29 April 2016Risk of concealed overdose is lower and could be measured more easily.Show More
Dear Editor
The authors consider that screening all deliberate overdose patients for an antidote requiring paracetamol overdose (ARPO) is justified. They cite the large study sample size (20,000) required to define the risk of concealed ARPO in a conscious co-operative patient, and estimate that this may be as low as 1/50
However, in this study and the six cited references it occurred in 0/946 (upper 95 %...
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