Emerg Med J 20:66-67 doi:10.1136/emj.20.1.66-b
  • Best evidence topic reports

Contraindications to thrombolysis in patients taking coumarins

  1. Andy Ashton, Senior Clinical Fellow,
  2. Stewart Teece, Clinical Research Fellow,
  3. K Mackway-Jones
  1. Department of Emergency Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK; kevin.mackway-jones{at}


      A short cut review was carried out to establish what level of INR was a contraindication to thrombolysis in patients taking warfarins. Altogether 296 papers were found using the reported search, but none presented any evidence to answer the clinical question. More research is needed in this area and, in the mean time, local advice should be followed.

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