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Emerg Med J 20:511-513 doi:10.1136/emj.20.6.511
  • Original Article

Randomised controlled trial of the onset of analgesic efficacy of dexketoprofen and diclofenac in lower limb injury

Table 3

Cumulative proportions of patients with a reduction in pain score over time and odds ratios for difference between study drugs

By 15 minutes By 30 minutes By 45 minutes By 60 minutes
Figures in parentheses are 95% confidence intervals unless stated.
Pain score reduction of ⩾1
Diclofenac 0.21 0.51 0.65 0.68
Dexketoprofen 0.42 0.78 0.89 0.92
p Value (χ2) 0.015 (5.86) 0.001 (10.24) 0.001 (10.42) <0.0001 (11.33)
Odds ratio for improvement with dexketoprofen compared with diclofenac 2.66 (1.19 to 5.98) 3.52 (1.60 to 7.73) 4.48 (1.72 to 11.65) 5.54 (1.90 to 16.15)
Pain score reduction of ⩾2
Diclofenac 0.04 0.16 0.19 0.26
Dexketoprofen 0.20 0.41 0.55 0.77
p Value (χ2) 0.005 (7.66) 0.001 (9.68) <0.001 (16.7) <0.001 (21.7)
Odds ratio for improvement with dexketoprofen compared with diclofenac 6.88 (1.48 to 32.0) 3.79 (1.59 to 9.01) 5.19 (2.29 to 11.78) 5.87 (2.68 to 12.88)

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