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Emerg Med J 2005;22:599-600 doi:10.1136/emj.2002.004036
  • Case report

Troponin for prediction of cardiovascular collapse in acute colchicine overdose

  1. C van Heyningen,
  2. I D Watson
  1. University Hospital Aintree, Liverpool, L9 7AL
  1. Correspondence to:
 Dr C van Heyningen
 University Hospital Aintree, Liverpool L9 7AL, UK; charles.vanheyningenaht.nwest.nhs.uk
  • Accepted 11 December 2003

Abstract

The use of colchicine, a treatment for acute gout and familial Mediterranean fever, is limited by its toxicity. A relatively low dose of colchicine may be fatal. After a colchicine overdose, monitoring should include 6–12 hourly serum troponin measurements. A rising troponin level predicts cardiovascular collapse and is an indication for more intensive management.

Footnotes

  • Competing interests: none declared

Responses to this article

  • Authors' response
    • Charles van Heyningen,
    • Ian D Watson
    Emerg Med J published online September 29, 2005
  • Serial Troponin-I measurements are unlikely to be useful in acute colchicine toxicity
    • David M WOOD,
    • Shaun L. GREENE, Paul I. DARGAN, Alison L. JONES
    Emerg Med J published online August 15, 2005

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