rss
Emerg Med J 2006;23:403-407 doi:10.1136/emj.2006.036608
  • Best evidence topic reports

Brain natriuretic peptide as a potential marker of acute coronary syndromes

  1. Richard Body, Clinical Research Fellow,
  2. Catherine Roberts, SHO, Emergency Medicine Rotation
  1. Manchester Royal Infirmary

      Abstract

      A short cut review was carried out to establish whether brain natriuretic peptide (BNP) can be used as a marker for acute coronary syndromes. 685 citations were found, of which eight presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are tabulated. The clinical bottom line is that BNP shows promise as an early cardiac marker and may enhance prognostic stratification. NPV and PPV may be unacceptably low to enable use as a sole cardiac marker. Incorporation into a multimarker strategy and serial estimations may be necessary.

      This Article

      1. Abstract
      2. Full text
      3. PDF

      Responses

      1. Submit a response
      2. No responses published

      Register for free content

      The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

      Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.