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Intranasal alfentanil for acute pain in children
  1. J Brenchley,
  2. S Ramlakhan
  1. Emergency Department, Barnsley District General Hospital, UK;

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    Traditionally, the intranasal analgesic drug of choice in children has been diamorphine. Prompted by the Department of Health bulletin in December 2004,1 warning of an impending shortage of diamorphine, we sought a viable alternative intranasal drug for providing analgesia for children with acute pain.

    Alfentanil has a favourable pharmacokinetic profile for nasal administration with maximal plasma concentrations at 9 minutes and …

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