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Traditionally, the intranasal analgesic drug of choice in children has been diamorphine. Prompted by the Department of Health bulletin in December 2004,1 warning of an impending shortage of diamorphine, we sought a viable alternative intranasal drug for providing analgesia for children with acute pain.
Alfentanil has a favourable pharmacokinetic profile for nasal administration with maximal plasma concentrations at 9 minutes and …
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