Abstract

Clozapine is a prototypical second-generation antipsychotic, which has been found to be associated with various adverse effects. Although emphasis has mainly been placed on its haematological and metabolic side effects, less attention has been paid to its anticholinergic effects. One such problem is that of a paralytic ileus. A case of a young man with psychosis who developed a paralytic ileus while on treatment with clozapine is described here.