Table 5
Sensitivity, specificity and likelihood ratios for each variable
| Feature | Sensitivity | Specificity | Positive likelihood ratio | Negative likelihood ratio |
| Male sex | 86/132 (65.2%) | 635/1444 (44.0%) | 1.16 (1.02 to 1.33) | 0.792 (0.623 to 1.01) |
| Nature of chest pain | ||||
| Indigestion/burning | 16/129 (12.4%) | 1307/1426 (91.7%) | 1.49 (0.91 to 2.43) | 0.956 (0.894 to 1.02) |
| Stabbing/sharp | 18/129 (14.0%) | 1133/1426 (79.5%) | 0.679 (0.437 to 1.06) | 1.08 (1.0 to 1.17) |
| Aching/dull/heavy | 59/129 (45.7%) | 774/1426 (54.3%) | 1.0 (0.822 to 1.22) | 1.0 (0.847 to 1.18) |
| Gripping/crushing | 25/129 (19.4%) | 1219/1426 (85.5%) | 1.33 (0.919 to 1.94) | 0.943 (0.864 to 1.03) |
| Non-specific/other | 11/129 (8.5%) | 1271/1426 (89.1%) | 0.784 (0.437 to 1.41) | 1.03 (0.971 to 1.08) |
| Site of chest pain | ||||
| Central | 101/131 (77.7%) | 424/1431 (29.6%) | 1.10 (0.992 to 1.21) | 0.773 (0.559 to 1.07) |
| Left chest | 18/131 (13.7%) | 1141/1431 (79.7%) | 0.678 (0.436 to 1.05) | 1.08 (1.01 to 1.16) |
| Right chest | 1/131 (0.8%) | 1396/1431 (97.6%) | 0.312 (0.043 to 2.26) | 1.02 (1.0 to 1.04) |
| Other | 11/131 (8.4%) | 1332/1431 (93.1%) | 1.21 (0.668 to 2.20) | 0.984 (0.933 to 1.04) |
| Radiation of chest pain | ||||
| None | 43/130 (33.1%) | 842/1404 (60.0%) | 0.826 (0.642 to 1.06) | 1.12 (0.982 to 1.27) |
| Left arm | 45/130 (34.6%) | 993/1404 (70.7%) | 1.18 (0.921 to 1.52) | 0.924 (0.812 to 1.05) |
| Right arm | 9/130 (6.9%) | 1374/1404 (97.9%) | 3.24 (1.57 to 6.68) | 0.951 (0.907 to 0.997) |
| Neck | 5/130 (3.8%) | 1331/1404 (94.8%) | 0.740 (0.304 to 1.80) | 1.01 (0.978 to 1.05) |
| Jaw | 3/130 (2.3%) | 1347/1404 (95.9%) | 0.568 (0.181 to 1.79) | 1.02 (0.990 to 1.05) |
| Back | 11/130 (8.5%) | 1241/1404 (88.4%) | 0.729 (0.407 to 1.31) | 1.04 (0.980 to 1.09) |
| Other | 14/130 (10.8%) | 1296/1404 (92.3%) | 1.40 (0.827 to 2.37) | 0.967 (0.909 to 1.03) |
| Time of onset | ||||
| 00:00–05:59 | 26/121 (21.5%) | 1060/1288 (82.3%) | 1.21 (0.847 to 1.74) | 0.954 (0.866 to 1.05) |
| 06:00–11:59 | 50/121 (41.3%) | 663/1288 (51.5%) | 0.852 (0.684 to 1.06) | 1.14 (0.973 to 1.34) |
| 12:00–17:59 | 24/121 (19.8%) | 1048/1288 (81.4%) | 1.06 (0.731 to 1.55) | 0.985 (0.898 to 1.08) |
| 18:00–23:59 | 21/121 (17.4%) | 1129/1288 (87.7%) | 1.41 (0.928 to 2.13) | 0.943 (0.867 to 1.03) |
| Continuous | 74/111 (66.7%) | 393/1192 (33.0%) | 0.995 (0.867 to 1.14) | 1.01 (0.768 to 1.33) |
| Nausea | 43/127 (33.9%) | 948/1394 (68.0%) | 1.06 (0.820 to 1.36) | 0.973 (0.854 to 1.11) |
| Vomiting | 9/125 (7.2%) | 1293/1376 (94.0%) | 1.19 (0.615 to 2.32) | 0.988 (0.939 to 1.04) |
| Sweating | 59/128 (46.1%) | 808/1393 (58.0%) | 1.10 (0.909 to 1.34) | 0.929 (0.787 to 1.10) |
| Dyspnoea | 49/126 (38.9%) | 822/1381 (59.5%) | 0.961 (0.765 to 1.21) | 1.03 (0.887 to 1.19) |
| Previous coronary heart disease | 16/127 (12.6%) | 1227/1407 (87.2%) | 0.985 (0.611 to 1.59) | 1.0 (0.935 to 1.07) |
| Diabetes | 7/128 (5.5%) | 1309/1396 (93.8%) | 0.878 (0.415 to 1.85) | 1.01 (0.965 to 1.05) |
| Hypertension | 52/129 (40.3%) | 975/1382 (70.5%) | 1.37 (1.09 to 1.71) | 0.846 (0.731 to 0.979) |
| Hyperlipidaemia | 37/118 (31.4%) | 937/1300 (72.1%) | 1.12 (0.848 to 1.49) | 0.952 (0.839 to 1.08) |
| Smoker | 36/126 (28.6%) | 944/1386 (68.1%) | 0.896 (0.673 to 1.19) | 1.05 (0.934 to 1.79) |
| Ex-smoker | 26/123 (21.1%) | 1145/1326 (86.3%) | 1.55 (1.07 to 2.24) | 0.913 (0.831 to 1.0) |
| Cocaine use | 0/122 (0%) | 1300/1323 (98.3%) | – | – |
| Family history | 48/119 (40.3%) | 706/1303 (54.2%) | 0.880 (0.702 to 1.10) | 1.10 (0.942 to 1.29) |
| Chest wall | 4/108 (3.7%) | 1181/1259 (93.8%) | 0.598 (0.223 to 1.60) | 1.03 (0.987 to 1.07) |
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Differences in denominators for sensitivity and specificity are due to missing data.
