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Rhabdomyolysis and the use of sodium bicarbonate and/or mannitol

Report by: Rachel Thomas, Medical Student

Search checked by: Jessi Cox, Medical Student

Institution: Oregon Health and Science University, Oregon, USA

Three-part question

In [patients with rhabdomyolysis and a CKMB >10 000] does the use of [intravenous sodium bicarbonate and/or mannitol] [decrease morbidity]?

Clinical scenario

A 36-year-old man presents to the Emergency Department (ED) following ingestion of one bottle of over-the-counter diphenhydramine. A friend found the patient lying down with the empty bottle next to him. …

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