Article Text

PDF
BET 3

Statistics from Altmetric.com

Rapid tranquilisation in acute psychotic agitation

Report by: Lawrie Hughes, Student, Dr Gordon Fuller, Academic Clinical Fellow

Search checked by: Dr Gordon Fuller, Academic Clinical Fellow

Institution: Manchester Royal Infirmary, Manchester, UK

Three-part question

In (adult patients agitated secondary to acute psychosis) is (IM olanzapine or IM haloperidol) better at (providing safe and effective sedation)?

Clinical scenario

An agitated 24-year-old patient with a history of schizophrenia enters the emergency department, and becomes aggressive and hostile towards staff and patients. De-escalation techniques fail, and the patient will not take oral medication or allow intravenous cannulation. You wonder whether intramuscular (IM) haloperidol or olanzapine is the best drug to rapidly, safely and effectively calm the patient.

Search strategy

Medline 1950 to October week 2 2010 using the OVID interface, EMBASE 1980 to week 24 2010 using …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Best evidence topic reports
    Simon D Carley
  • Best evidence topic reports
    BMJ Publishing Group Ltd and the British Association for Accident & Emergency Medicine
  • Best evidence topic reports
    BMJ Publishing Group Ltd and the British Association for Accident & Emergency Medicine
  • Best Evidence Topic reports
    BMJ Publishing Group Ltd and the British Association for Accident & Emergency Medicine