Statistics from Altmetric.com
Do bisphosphonates relieve pain caused by acute osteoporotic vertebral compression fractures?
Institution: City Hospital, Birmingham, UK
A 72-year-old woman presents to the emergency department with severe back pain after a mechanical fall. Plain radiographs of her thoracic spine show osteopenic vertebrae with a wedge compression fracture of the body of T8. Her pain is controlled acutely with paracetamol, ibuprofen and oral morphine sulphate. She is mobilised and arrangements are made for her to have physiotherapy in the community. You are keen to discharge this patient but want to maintain pain control and, given the potential side effects, would prefer to avoid opiates and non-steroidals. You have heard that some bisphosphonates relieve the pain of pathological fractures and wonder whether they do so in vertebral compression fractures.
In [patients with osteoporotic vertebral compression fractures] do [bisphosphonates] reduce [pain]?
MEDLINE 1950–November Week 2, 2010; EMBASE 1980–2010, Week 46 and the Cochrane Library November 2010.
MEDLINE and EMBASE: exp fractures, compression/OR exp spinal …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.