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Prospective cohort study a clinical diagnosis of severe sepsis or septic shock
Thenar muscle tissue oxygen saturation (StO2) on arrival in the emergency department (ED) and its change with usual ED sepsis management was measured using near-infrared spectroscopy, and a follow-up measurement was obtained after 24 h of treatment. All surviving patients were followed up for 30 days. Forty-nine patients were included and 24 died. There was no difference in mean StO2 on arrival in the ED between survivors and non-survivors. After ED treatment, mean StO2 of survivors improved significantly to 78% while StO2 remained persistently low in non-survivors. Persistently low StO2 (<75%) despite initial resuscitative treatment was associated with a twofold increase in mortality (see page 699).
Remote specialist assessment by telephone of intravenous thrombolysis for acute ischaemic stroke
The study was a retrospective cases series from three EDs within a single stroke service in …
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