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Three-part question
Patient group—(In adults admitted to the ED with an out-of-hospital cardiac arrest)
Intervention—(does end tidal CO2 measurement)
Outcome—(predict/prognosticate return of spontaneous circulation)?
Clinical scenario
A 60-year-old male is brought into the ED with an
out-of-hospital cardiac arrest (OOHCA). All monitoring is attached while ALS protocol is ongoing, including CO2 monitoring. You want to assess whether the patient is going to survive and thereby achieve a return of spontaneous circulation (ROSC) and you wonder whether the patient’s end tidal CO2 (ETCO2) level can prognosticate this.
Search strategy
Medline, Cochrane and EMBASE databases (2006 to present).
[exp HEART ARREST/ or "Heart arrest".ti,ab or "cardiac arrest".ti,ab] AND [ETCO2.ti,ab or "end tidal co2".ti,ab or exp CAPNOGRAPHY/ or capnometry.ti,ab or {exp CARBON DIOXIDE/ AND exp TIDAL VOLUME/ AND 19 AND 20}] AND [{exp SURVIVAL/ OR exp SURVIVAL ANALYSIS/} or exp TREATMENT OUTCOME/ or {(rosc …