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Capillary and Venous Lactate Agreement: a pilot prospective observational study
  1. Deepankar Datta1,
  2. Julia Grahamslaw1,
  3. Alasdair James Gray1,
  4. Catriona Graham2
    1. 1Emergency Medicine Research Group Edinburgh, Department of Emergency Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK
    2. 2Wellcome Trust Clinical Research Facility, Western General Hospital, Edinburgh, UK
    1. Correspondence to Dr Deepankar Datta, Emergency Medicine Research Group Edinburgh, Department of Emergency Medicine, Royal Infirmary of Edinburgh, Little France Crescent, Edinburgh EH16 4SA, UK; deepankardatta{at}nhs.net

    Abstract

    Background Blood lactate is a marker of patient illness severity. Capillary lactate (CAP-LACT) measurement can potentially improve patient screening; however, it has poor evidence of clinical utility.

    Aim We aimed to investigate agreement between CAP-LACT and peripheral venous lactate (PV-LACT).

    Methods We performed a prospective observational pilot study of 99 patients requiring lactate measurement. Paired CAP-LACT and PV-LACT was recorded. Agreement was determined by Bland-Altman analysis.

    Results Bias was 0.2 mmol/L, with 95% limits of agreement from −1.9 to 2.3.

    Conclusions CAP-LACT has poor agreement with PV-LACT. Further research is needed to improve its potential clinical utility.

    • equipment evaluation
    • assessment
    • clinical care

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