Article Text

other Versions

PDF
Human factors in prehospital research: lessons from the PARAMEDIC trial
  1. Helen Pocock1,
  2. Charles D Deakin1,2,
  3. Tom Quinn3,
  4. Gavin D Perkins4,5,
  5. Jessica Horton4,
  6. Simon Gates4
  1. 1South Central Ambulance Service NHS Foundation Trust, Otterbourne, UK
  2. 2NIHR Southampton Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, UK
  3. 3Faculty of Health, Social Care and Education, Kingston University and St George's, University of London, London, UK
  4. 4Warwick Clinical Trials Unit, University of Warwick, Coventry, UK
  5. 5Heart of England NHS Foundation Trust, Birmingham, UK
  1. Correspondence to Helen Pocock, South Central Ambulance Service NHS Foundation Trust, c/o Bracknell Ambulance Station, Old Bracknell Lane West, Bracknell, Berkshire RG12 7AE, UK; helen.pocock{at}scas.nhs.uk

Abstract

Background There is an urgent need to develop prehospital research capability in order to improve the care of patients presenting to emergency medical services (EMS). The Prehospital Randomised Assessment of a Mechanical compression Device In Cardiac arrest trial, a pragmatic cluster randomised trial evaluating the LUCAS-2 device, represents the largest randomised controlled trial conducted by UK ambulance services to date. The aim of this study was to identify and analyse factors that may influence paramedic attitudes to, and participation in, clinical trials.

Methods Personal and organisational experience from this trial was assessed by feedback from a workshop attended by collaborators from participating EMS and a survey of EMS personnel participating in the trial. A work systems model was used to explain the impact of five interwoven themes—person, organisation, tasks, tools & technology and environment—on trial conduct including gathering of high-quality data.

Results The challenge of training a geographically diverse EMS workforce required development of multiple educational solutions. In order to operationalise the trial protocol, internal organisational relationships were perceived as essential. Staff perceptions of the normalisation of participation and ownership of the trial influenced protocol compliance rates. Undertaking research was considered less burdensome when additional tasks were minimised and more difficult when equipment was unavailable. The prehospital environment presents practical challenges for undertaking clinical trials, but our experience suggests these are not insurmountable and should not preclude conducting high-quality research in this setting.

Conclusions Application of a human factors model to the implementation of a clinical trial protocol has improved understanding of the work system, which can inform the future conduct of clinical trials and foster a research culture within UK ambulance services.

Trial registration number ISRCTN08233942.

  • pre-hospital
  • cardiac arrest
  • research, operational
  • research, clinical
  • resuscitation

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.