Table 4

Author, date and countryPatient groupStudy type (level of evidence)OutcomesKey resultsStudy weaknesses
Fitzgerald D et al, 1996, Australia66 hospitalised children with viral or spasmodic croup.PRCTChange in total croup symptom score7.1 (1.2) v 7.7 (1.1) (not significant)Sample size calculated to be 66 but only 53 completed the 24 h study.
Duration of croup attack in hours31 (21) v 26 (21) (not significant)
Budesonide 2 mg v epinephrine 4 mgSide effectsNo significant differenceNo follow up