Author, date and country | Patient group | Study type (level of evidence) | Outcomes | Key results | Study weaknesses |
---|---|---|---|---|---|
Fitzgerald D et al, 1996, Australia | 66 hospitalised children with viral or spasmodic croup. | PRCT | Change in total croup symptom score | 7.1 (1.2) v 7.7 (1.1) (not significant) | Sample size calculated to be 66 but only 53 completed the 24 h study. |
Duration of croup attack in hours | 31 (21) v 26 (21) (not significant) | ||||
Budesonide 2 mg v epinephrine 4 mg | Side effects | No significant difference | No follow up |