| Author, date and country | Patient group | Study type (level of evidence) | Outcomes | Key results | Study weaknesses |
|---|---|---|---|---|---|
| Brahma AK et al UK, 1996 | 401 patients with corneal abrasion | PRCT | Difference in pain score over 24 hour period and use of oral analgesia | No difference between homatrapine and simple lubrication. No difference between the 2 groups receiving flubriprofen | Only 55% of patients followed up. |
| Lubrication alone v 2% homatrapine (single dose) v flubiprofen 0.03% QDS v flubiprofen 0.03% qds and homatropine stat | All patients also received chloramphenicol ointment. | ||||
| Study not blinded |