Table 2
Author, date and countryPatient groupStudy type (level of evidence)OutcomesKey resultsStudy weaknesses
Vretnar DF et al, 1994, Canada68 hypothermic patients with a mean core temperature of 21°C of whom 61 were in cardiac arrest.ReviewOverall survival60%Publication bias likely as success more likely to be reported than failure.
All patients placed on cardiopulmonary bypassSurvival if core temperature <15 degrees0%
Data derived from 34 reports.Return to previous function60% of survivors
Koller R et al, 1997, Switzerland5 patients with core temperature below 30°C of whom 2 were in cardiac arrestCohortOverall survival100%Small numbers.
Return to previous function100%
Walpoth BH et al, 199732 of 46 patients in cardiac arrest with core temperature below 28°CProspective cohortOverall survival15/32 (45%)Unclear why patients selected for bypass
All patients placed on cardiopulmonary bypass