Table 9
Author, date and countryPatient groupStudy type (level of evidence)OutcomesKey resultsStudy weaknesses
Teasdale GM et al, 1990, GlasgowSub group in paper of 99 head injured children requiring neurosurgeryMulticentred prospective comparativeFully conscious and no skull fracture16% of those with ICI 0.5% of all attendees with head injury in this category Incomplete data Not restricted to mild trauma
Impaired consciousness and no skull fracture12% of those with ICI 7.6% of all attendees in this category
Dietrich AN et al, 1993, USAAll head trauma children scanned in 12 month period n=322, mean age of 7.1 years 20% <2 years oldProspective cohortCT results12% with ICINot restricted to mild trauma
Clinical factorsAmnesia for event highest sensitivity of 87%. LOC less sensitive at 68%. Abscence of amnesia, LOC, focal neurology and headache >89% negative predictive valueNot clear if all head trauma seen was scanned
Not clear if truly prospective
M & M5% of those with ICI had evacuation of haematoma. 13% diedIncomplete clinical data No available data on interventions required for those with minor head injury
Quayle KS et al, 1997, USA322 `non-trivial' head injuriesProspective cohortImaging8.4% had ICI410 children originally identified as `non-trivial'
Surgical follow up59% (16) of those with ICI GCS of 15 and no focal neurology, 1 of whom required neurosurgery. 6 of these asymptomatic children were <1 year (5/6 had scalp haematoma). Four-fold increase of intracranial haematoma with skull fractureSelective and incomplete data collection on subgroup
Not restricted to mild trauma
Greenes DS and Schutzman SA, 1999, USA608 infants <2 years (11.2 +/− 6.8 months. 57% male) with head traumaProspective (selected CT scan)CT result16% of those imaged shown to have ICIReal rate of ICI injury on CT probably underestimated as only 31% had CT following pre-existing ED protocol
Clinical factors in CT proven ICIHalf of those with ICI had no symptoms. Significantly more ICI in infants <3 months
Age93% of infants who were asymptomatic with ICI had scalp haematoma (77% of those with ICI overall)GCS not given
Not restricted to minor injury
Scalp haematoma13% of infants with ICI had evacuation of haematoma
M & MNo deaths
Two week follow upNo CT's ordered for those not imaged originally, no clinical deterioration for those who had a normal CT originally
Wang MY et al, 2000, USA157 of 209 children with GCS of 13–14 as assessed by paramedic at scene transported to trauma centre and were CT scannedProspective multicentreHead CT19.1% had ICI, half of whom had no skull fractureData not available for 52 patients
Difference in GCSNo significant difference in ICI or skull fracture between GCS 13 and 14No data on focal neurology
Change in GCS60% of those with ICI had an improvement in GCS on re-examination (ie >13)
Loss of consciousness67% of those with ICI had no history of LOC
M & M3.2% had haematoma evacuation, one of whom required long term rehabilitation. All lived