| Bosse GM et al, 1995, USA | 51 patients presenting with tricyclic overdose. | RCT | Mean length of stay | 93.3 (+/− 94.3) hours v 107.2 (+/− 106.8) hours v 66.7 (+/− 41.7) hours (p=0.473) | Not blinded |
| | | | | Small numbers |
| Charcoal only (n=22) v charcoal then lavage (n=14) v charcoal then lavage then charcoal (n=15) | | Mean length ICU stay | 66.9 (+/− 96.0) hours v 54.1 (+/− 34.3) hours v 34.4 (+/− 27.3) hours (p=0.436) | Variations between presenting GCS and drug levels between groups |
| 39 intubated | | Mean mechanical ventilation time | 43.4 (+/− 17.7) hours v 24.1 (+/− 18.3) hours v 17.8 (+/− 14.0) hrs (p=0.321) | |
| | | Aspiration | 2/22 v 3/14 v 3/15 (p=0.501) | |