Table 5

Author, date and countryPatient groupStudy type (level of evidence)OutcomesKey resultsStudy weaknesses
Sheikh A et al, 1999, UK527 patients, from 3 studies, with acute bacterial conjunctivitis randomised to receive either topical antibiotic preparation or placeboMeta-analysisEarly (days 2–5) clinical remissionRR 1.31 (99% CI 1.11 to 1.55)Inclusion criteria of swab proven acute bacterial conjunctivitis in only 2 of the 3 studies
Late (days 6–10) clinical remissionRR 1.27 (99% CI 0.92 to 1.74)Different topical antibiotic preparations in each of the 3 studies
Selected specialist care patient populations