| Ronning OM and Guldvog B, 1999, Norway | 550 patients presenting within 24 hours after stroke onset | RCT (randomised on birth dates) | Disability at seven months (Barthel Index) | No difference between the two groups on disability (p = 0.07) or impairment scores (p = 0.67) | Quasi-randomised |
| Exclusion criteria: age<60, onset>24 hours, subdural, subarachnoid, TIA | Impairment at seven months (Scandinavian Stroke Scale) Survival at one year | No statistical significant difference (p = 0.3) in survival rates | Effects of being treated in a stroke unit |
| Supplemental oxygen v no oxygen | One year survival greater in control group (72.9% v 68.8%) |