| Verma SP et al, 1989, UK | 36 male patients with acute LVF secondary to recent MI (<10 hours) in CCU | PRCT | Left heart filling pressures | All three groups reduced | Only 36 patients |
| IV v buccal v transdermal GTN | | Cardiac output | No reduction in any group | Different doses of buccal, IV and dermal GTN (based on previous studies) |
| | | BP | 3 patients had BP falls in buccal group but with no clinical deterioration | |
| Average doses over 90 min: IV 12.9 mg, buccal 5 mg, dermal 20 mg | | | | IV dose individually titrated; buccal and dermal doses predetermined |