| Danel V et al, 1988, UK | 12 healthy volunteers given 1.5 g aspirin acting as own controls treated with nothing, charcoal and lavage | Prospective controlled study | Salicylate recovered in urine over 24 h | Control 13.3% lavage 8.8% charcoal 7.0% | Statistical significance not assessed |
| Dose fairly small |
| Number of patients small |
|
| Lapatto-Reiniluoto O et al, 1999, Finland | Nine healthy volunteers as own controls given 400 mg ibuprofen. Treated with water (control), charcoal or charcoal followed by lavage | Prospective controlled trial | AUC plasma ibuprofen as % of control | Control 100% charcoal alone 70% (p<0.05) charcoal + lavage 51% (p<0.05). No statistical significance between control groups | Small numbers |
| Therapeutic ibuprofen dose |