Table 1 Characteristics of studies of intravenous magnesium sulphate
StudyLocationPublication yearTotal sampleAge range (years)Sex %F:MAsthma severityJadad scoreReported outcomes
BijaniIran20028112–8547:53Acute exacerbation3PEFR and asthma score
SilvermanUSA200224818–6042:58Severe5PEFR*, FEV1, Borg index and admissions
PorterUSA20014218–5564:36Moderate–severe5PEFR, L admissions and Borg index
BilacerogluTurkey20018116–6569:31Moderate–severe2†FEV1 (% predicted) and admissions
BoonyavorakulThailand20003315–6588:12Severe5Admissions and Fischl index
ScarfoneUSA2000541–1848:52Moderate–severe5Admissions and pulmonary index score
CiaralloUSA2000306–1840:60Moderate–severe4PEFR (change in % predicted)*, FEV1, FVC and admissions
GurkanTurkey1999206–1645:55Moderate– severe3PEFR (% change from baseline)* and asthma score
DeviIndia1997471–1223:77Severe4PEFR (% predicted) and pulmonary index score
CiaralloUSA1996316–1855:45Moderate–severe4PEFR (% change from baseline)*, FEV1, FVC and admissions
BlochUSA199513518–6572:28Moderate–severe5FEV1 (% predicted), Borg index and admissions
MatusiewiczUK1994129>1657:42Moderate–life threatening5PEFR and admissions
TiffanyUSA19934818–6059:41Severe4PEFR* and FEV1
GreenUSA199212018–6577:23Acute exacerbation1PEFR and admissions
SkobeloffUSA19893818–7074:26Moderate–severe5PEFR and admissions
  • FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; PEFR, peak expiratory flow rate.

  • *When more than one pulmonary function test was used, the measure marked with an asterisk was used in analysis.

  • †Based on abstract alone.