Children given concomitant medicines in the DIASAFE study
| Concomitant Medications | No. of patients | Percentage of total patients* |
|---|---|---|
| Patients given medication post-IND | 100 | 44.4 |
| Painkillers | ||
| Paracetamol | 47 | 20.8 |
| Ibuprofen | 44 | 19.5 |
| Entonox | 20 | 8.8 |
| Diclofenac | 1 | 0.4 |
| Opiate (non-IMP) | 10 | 4.4 |
| Asthma treatment | ||
| Salbutamol | 6 | 2.7 |
| Beclometasone | 4 | 1.8 |
| Fluticasone | 1 | 0.4 |
| Antihistamine (chlorpheniramine) | 2 | 0.9 |
| Other | ||
| Topical/local anaesthetic | 7 | 3.1 |
| Antibiotic | 6 | 2.7 |
| Midazolam | 1 | 0.4 |
| Ketamine | 3 | 1.3 |
*To 1 decimal place.
IMP, investigational medicinal product; IND, intranasal diamorphine.