Demographics and characteristics of study patients 2009–2013
| Non-warfarinised patients (n=136 118) | Warfarinised patients (n=499) | p Value | Unadjusted OR (95% CI) | |
|---|---|---|---|---|
| Age median (IQR) | 58.1 (38.9–77.1) | 80.2 (70.3–85.4) | <0.001 | 1.05 (1.04 to 1.06) |
| ISS median (IQR) | 9 (9–17) | 13 (9–25) | <0.001 | 1.02 (1.01 to 1.03) |
| GCS 3–8, n (%) | 7925 (6.5%) | 39 (7.8%) | 0.110 | 1.31 (0.94 to 1.83) |
| GCS 9–14, n (%) | 19 349 (16%) | 108 (21.6%) | <0.001 | 1.49 (1.20 to 1.84) |
| Women, n (%) | 55 695 (40.9%) | 220 (44.1%) | 0.151 | 1.40 (0.95 to 1.36) |
| Head injury, n (%) | 34 169 (25.1%) | 212 (42.5%) | <0.001 | 2.20 (1.84 to 2.63) |
| Specialist neuro centre, n (%) | 52 012 (38.2%) | 290 (58.1%) | <0.001 | 2.24 (1.88 to 2.68) |
| PMC yes, n (%) | 75 452 (55.4%) | 494 (99%) | <0.001 | 46.5 (19.3 to 112.6) |
| PMC not known, n (%) | 25 176 (18.5%) | 0 (0%) | N/A* | N/A* |
| 30-day mortality, n (%) | 9622 (7.1%) | 112 (22.4%) | <0.001 | 3.80 (3.08 to 4.70) |
*No case recorded for warfarinised group to make comparison.ISS, Injury Severity Score; PMC, pre-existing medical condition.