Prognostic accuracy of scoring systems (95% CI) for predicting inhospital death and ICU admission in patients with suspected sepsis
| qSOFA | SIRS | NEWS | |
| Inhospital death | |||
| Sensitivity, % | 37 (31 to 43) | 80 (74 to 84) | 74 (68 to 79) |
| Specificity, % | 79 (77 to 81) | 21 (19 to 23) | 43 (41 to 46) |
| Positive predictive value, % | 23 (19 to 28) | 15 (13 to 17) | 18 (16 to 21) |
| Negative predictive value, % | 88 (86 to 90) | 86 (82 to 89) | 91 (88 to 93) |
| Positive likelihood ratio | 1.78 (1.48 to 2.14) | 1.01 (0.94 to 1.08) | 1.30 (1.19 to 1.41) |
| Negative likelihood ratio | 0.80 (0.72 to 0.88) | 0.96 (0.75 to 1.25) | 0.61 (0.55 to 0.61) |
| AUROC | 0.62 (0.59 to 0.66) | 0.49 (0.45 to 0.52) | 0.65 (0.61 to 0.68) |
| ICU admission | |||
| Sensitivity, % | 36 (23 to 50) | 85 (72 to 93) | 77 (64 to 88) |
| Specificity, % | 77 (75 to 79) | 21 (19 to 23) | 41 (39 to44) |
| Positive predictive value, % | 5 (3 to 7) | 3 (2 to 4) | 4 (3 to 5) |
| Negative predictive value, % | 98 (97 to 98) | 98 (96 to99) | 99 (97 to 99) |
| Positive likelihood ratio | 1.57 (1.09 to 2.28) | 1.08 (0.96 to 1.21) | 1.32 (1.13 to 1.53) |
| Negative likelihood ratio | 0.83 (0.68 to 1.02) | 0.71 (0.37 to 1.36) | 0.55 (0.33 to 0.90) |
| AUROC | 0.59 (0.52 to 0.67) | 0.54 (0.47 to 0.61) | 0.64 (0.57 to 0.71) |
All analyses except AUROC used thresholds of qSOFA ≥2, SIRS≥2 and NEWS≥5.
AUROC, area under the receiver operating characteristics curve; ICU, intensive care unit; NEWS, National Early Warning Score; qSOFA, quick Sequential Organ Failure Assessment; SIRS, Systemic Inflammatory Response Syndrome.