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Fehlbildungen bei Kaninchen nach hyperbarer Oxygenation

Malformations in rabbit embryos after hyperbaric oxygen

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Summary

At the 9th day of gestation pregnant rabbits were exposed to an oxygen pressure of 1.5 or 2.0 ata (absolute atmospheres) for 5 hours.

The mother rabbits were killed on the 29th day of pregnancy. The foetuses were removed and the uteri studied for resorptions. After macroscopic inspection, skeleton preparations were made and inspected for malformations. The results were compared with untreated controls. Hyperbaric oxygen resulted in increased resorption rate and number of malformations.

Zusammenfassung

Gravide Kaninchen wurden am 9. Tag der Gestation für 5 Std einem Sauerstoffdruck von 1,5 oder 2,0 absoluten Atmosphären ausgesetzt. Die Druckexposition führte zu einem Anstieg der Resorptionsrate und der Mißbildungsfrequenz.

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Authors and Affiliations

  1. Institut für Humangenetik und Anthropologie der Universität Düsseldorf, Germany

    W. Grote & W. D. Wagner

Authors
  1. W. Grote
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  2. W. D. Wagner
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Der Deutschen Forschungsgemeinschaft danken wir für die Unterstützung.

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Grote, W., Wagner, W.D. Fehlbildungen bei Kaninchen nach hyperbarer Oxygenation. Klin Wochenschr 51, 248–250 (1973). https://doi.org/10.1007/BF01467776

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  • DOI: https://doi.org/10.1007/BF01467776

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