Brief report
Atrial fibrillation induced by adenosine triphosphate

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Cited by (34)

  • Value of adenosine test to reveal dormant conduction or adenosine-induced atrial fibrillation after pulmonary vein isolation

    2017, Journal of Arrhythmia
    Citation Excerpt :

    Since the group without adenosine test is supposed to include similar ratio of patients (15%) with possible dormant conduction or induced AF (8%), AF recurrence rate probably can be prevented by durable PVI or elimination of non-PV triggers. It has been shown that adenosine can induce AF in humans [19]. The true mechanism is unclear, but previous studies speculated that adenosine-induced AF might have the same mechanism with vagally-mediated AF, since adenosine and acetylcholine's cellular electrophysiological effects are mediated by an identical signal transduction cascade to induce significant antiadrenergic effects [8,20].

  • A case of paroxysmal atrial fibrillation with a non-pulmonary vein trigger identified by intravenous adenosine triphosphate infusion

    2015, Journal of Arrhythmia
    Citation Excerpt :

    Several studies have indicated that an intravenous injection of adenosine, in the form of adenosine triphosphate (ATP), can induce the transient reconnection of isolated PVs after electric isolation, consistent with unmasking dormant conduction between the PVs and the left atrium (LA) [4,5]. Furthermore, ATP, when given as an intravenous bolus, can induce AF [6]. In addition, several studies have recently described the usefulness of an ATP injection for inducing and identifying PV and/or non-PV triggers after circumferential pulmonary vein ablation (CPVI) [7,8].

  • Adenosine in the treatment of supraventricular tachycardia: 5 years of experience (2002-2006)

    2008, American Journal of Emergency Medicine
    Citation Excerpt :

    This experience emphasizes what was reported in the Cochrane review [2], that is, that adenosine lacks any serious side effects when patients are selected appropriately and that the life-threatening alterations in heart rate that have been reported after the use of this drug [7-9] are extremely rare and generally due to improper use. These latter events were previously reported as being a proarrhythmic effect of adenosine, especially when it was used for diagnostic purposes [10-12]. Adenosine has proved to be of diagnostic value in both narrow and broad complex tachycardias [13-18] for understanding the mechanism of tachycardia itself [3,19].

  • Drug-induced atrial fibrillation

    2004, Journal of the American College of Cardiology
    Citation Excerpt :

    Adenosine can induce AF by the shortening of atrial action potential duration while it is used for terminating atrioventricular re-entry tachycardia. Most patients convert to SR within a few minutes (21–23), but also a case has been documented that needed electrical cardioversion (24). Case reports and experiments suggest that the calcium-channel blockers verapamil (25–27) and diltiazem (28) may aggravate or induce AF in susceptible patients.

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